PQM-1DAF-16,DAF-2寿DAF-16

Ronald G Tepper1, Jasmine Ashraf2, Rachel Kaletsky2

  • 1Department of Biological Sciences, Columbia University, New York, NY 10027, USA.

Cell
|August 6, 2013
PubMed
まとめ

減少したインスリン/IGF-1類似シグナル伝達 (IIS) は,遺伝子発現を変化させることで寿命を延長します. この研究は,PQM-1を発達遺伝子を制御する重要な要因として特定し,ストレスと老化を調節する DAF-16 との敵対的な関係を明らかにしています.

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