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Updated: May 8, 2026

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
13:08

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay

Published on: September 9, 2012

4因子プロトロンビン複合体の濃縮剤の有効性と安全性,大出血を伴うビタミンKアンタゴニストを服用している患者:ランダム化,プラズマ制御,第IIIb相試験

Ravi Sarode1, Truman J Milling, Majed A Refaai

  • 1University of Texas Southwestern Medical Center, Dallas (R.S.); Seton/University of Texas Southwestern Clinical Research Institute of Austin, Dell Children's Medical Center, University Medical Center at Brackenridge, Austin, TX (T.J.M.); University of Rochester Medical Center, Rochester, NY (M.A.R.); CSL Behring LLC, King of Prussia, PA (A.M., B.L.D.); CSL Behring GmbH, Marburg, Germany (A.S.); and Massachusetts General Hospital, Boston (J.N.G.).

Circulation
|August 13, 2013
PubMed
まとめ

4要素プロトロンビン複合物濃縮剤 (4F-PCC) は,主要な出血イベントにおけるビタミンK抗体療法を効果的に逆転させます. この研究は,4F-PCCが緊急の逆転のためにプラズマの安全で効果的な代替品であることを実証し,劣らずの血静効果と優れたINR補正を示しています.

キーワード:
抗凝固剤 (抗凝固剤) とは出血の出血は,出血によるものです.プラズマ・プラズマ・プラズマ・プラズマとはプロトロンビン複合体の濃縮物ビタミンKアンタゴニストである.

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