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Updated: May 8, 2026

Crystal Structure of the N-terminal Domain of Ryanodine Receptor from Plutella xylostella
11:31

Crystal Structure of the N-terminal Domain of Ryanodine Receptor from Plutella xylostella

Published on: November 30, 2018

分子混雑は,本質的に乱れた無カルシウム状態と,重複中毒素 (RTX) タンパク質の折りたたまれたカルシウム結合状態の両方を安定させます

Ana-Cristina Sotomayor-Pérez1, Orso Subrini, Audrey Hessel

  • 1Unité de Biochimie des Interactions Macromoléculaires, CNRS UMR 3528, Département de Biologie Structurale et Chimie, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris cedex 15, France.

Journal of the American Chemical Society
|August 15, 2013
PubMed
まとめ

マクロ分子混雑は,RC ((L)) のようなRTXタンパク質のカルシウム結合と安定性を高めます. 乱れた状態 (アポ) と折れた状態 (ホロ) の両方で観察されたこの効果は,混雑がタンパク質の輸出と細胞内の機能に影響することを示唆しています.

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X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep105011:27

X-Ray Crystallography to Study the Oligomeric State Transition of the Thermotoga maritima M42 Aminopeptidase TmPep1050

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