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Updated: May 8, 2026

Interactions with and Membrane Permeabilization of Brain Mitochondria by Amyloid Fibrils
15:04

Interactions with and Membrane Permeabilization of Brain Mitochondria by Amyloid Fibrils

Published on: September 28, 2019

リピド二重層は,2つの異なるアミロイド原性ペプチドの交叉動を著しく調節する

Noga Gal1, Ahiud Morag, Sofiya Kolusheva

  • 1Department of Chemistry, Ben Gurion University of the Negev , Beer Sheva, Israel 84105.

Journal of the American Chemical Society
|August 20, 2013
PubMed
まとめ

誤った折りたたまれたタンパク質は,アルツハイマー病などの病気でアミロイドプラークを形成します. この研究では,関係のないアミロイドペプチド,アイレットアミロイドポリペプチド (IAPP),プリオンタンパク質 (PrP) が膜に相互作用し,フィブリレーションと病原性を変化させることが示されています.

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