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Updated: May 8, 2026

Generation of a RIP1 Knockout U937 Cell Line Using the CRISPR-Cas9 System
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Generation of a RIP1 Knockout U937 Cell Line Using the CRISPR-Cas9 System

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病原体は,アルギニンによる宿主死亡受容体シグナリングをブロックし,死亡ドメインのGlcNAcylationを誘導する

Shan Li1, Li Zhang, Qing Yao

  • 1College of Biological Sciences, China Agricultural University, Beijing 100094, China.

Nature
|August 20, 2013
PubMed
まとめ

Enteropathogenic Escherichia coliは,死領域を改変し,NF-κB,アポプトシス,そしてネクロプトシスのような重要な細胞シグナル伝達経路をブロックすることによって,宿主の免疫反応を抑制するためにNleBを使用します. N-アセチルグルコサミントランスファーゼの活性を含むこの細菌のメカニズムは,感染に不可欠です.

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