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Updated: May 5, 2026

Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice
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変形成長因子-βのシグナリングは,Schistosoma mansoniによって引き起こされる肺高血圧を促進します

Brian B Graham1, Jacob Chabon, Liya Gebreab

  • 1Program in Translational Lung Research, Division of Pulmonary Sciences and Critical Care Medicine (B.B.G., J.C., L.G., J.P., E.D., L.D., T.T., L.S., N.D., R.W.V.) and Department of Pathology (X.-J.W.), Anschutz Medical Campus, Aurora, CO; Pulmonary Vascular Research Institute (B.B.G., A.B., H.C.C., G.B., R.M.T.); Memorial S. Jose Hospital, Universidade de Pernambuco in Recife, Recife, Brazil (A.B.); Division of Cardiology, University of Pittsburgh, Pittsburgh, PA (H.C.C.); School of Pharmacy, University of Kent, Kent, UK (G.B.); and Immunopathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD (T.A.W.).

Circulation
|August 21, 2013
PubMed
まとめ

統合失調症による肺動脈高血圧は,成長因子β (TGF-β) 信号伝達の変換を伴う. TGF-β経路の阻害は,マウスの疾患発症から保護され,治療目標を示唆しています.

キーワード:
高血圧,肺動脈高血圧などです.スキストソミアシス (Schistosomiasis) とは成長因子ベータを変換する.

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