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Updated: May 8, 2026

Multi-enzyme Screening Using a High-throughput Genetic Enzyme Screening System
08:10

Multi-enzyme Screening Using a High-throughput Genetic Enzyme Screening System

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新しいデアミナーゼ酵素の構造主導の発見

Daniel S Hitchcock1, Hao Fan, Jungwook Kim

  • 1Department of Biochemistry & Biophysics and ‡Department of Chemistry, Texas A&M University , College Station, Texas 77843, United States.

Journal of the American Chemical Society
|August 24, 2013
PubMed
まとめ

この研究は,アミドヒドロラゼ超家族内の未知の機能を持つ酵素を特定し,特徴づけるために,構造主導のアプローチを使用しています. 研究者らは,様々なアデノシンアナログと損傷したアデニン形態のデアミネーションを含む新しい酵素活動を発見し,タンパク質アノテーションを支援しました.

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