サーカディアン遺伝子のBmal1は,Ly6C(hi) 炎症性モノサイトの昼間振動を調節する

Khoa D Nguyen1, Sarah J Fentress, Yifu Qiu

  • 1Cardiovascular Research Institute, University of California, San Francisco, CA 94158-9001, USA.

Science (New York, N.Y.)
|August 24, 2013
PubMed
まとめ

サーカディアン遺伝子Bmal1は,炎症性単細胞の昼間リズムを調節し,感染部位への移動を制御します. Bmal1を阻害すると,免疫反応が低下し,炎症が促進されます.

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