Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Dementia01:30

Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual.
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Recurrence or persistence of atrial fibrillation is associated with frailty and adverse outcomes: the SAGE-AF cohort study.

BMC geriatrics·2026
Same author

The prevalence and burden of chronic kidney disease, patterns of anticoagulation prescribing, and major bleeding risk in older adults with atrial fibrillation.

BMC geriatrics·2025
Same author

Need for Engagement in Stroke Prevention Shared Decision-Making in Older Adults with Atrial Fibrillation and Multimorbidity.

Advances in geriatric medicine and research·2025
Same author

Fazekas score predicts cognitive decline & frailty in older adults: insights from the SAGE-AF cohort study.

Neurological research and practice·2025
Same author

Multiclass Arrhythmia Classification Using Multimodal Smartwatch Photoplethysmography Signals Collected in Real-Life Settings.

IEEE transactions on bio-medical engineering·2025
Same author

Multiclass arrhythmia classification using multimodal smartwatch photoplethysmography signals collected in real-life settings.

Research square·2024

関連する実験動画

Updated: May 8, 2026

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
06:52

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Published on: September 30, 2020

高齢者における妄想症

Sharon K Inouye1, Rudi G J Westendorp2, Jane S Saczynski3

  • 1Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA; Aging Brain Center, Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA.

Lancet (London, England)
|September 3, 2013
PubMed
まとめ

Deliriumは,高齢者の一般的な深刻な急性認知障害であり,正式な診断が必要です. 薬物治療には証拠が不足しているため,非薬学的予防が最も効果的です.

さらに関連する動画

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

関連する実験動画

Last Updated: May 8, 2026

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
06:52

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Published on: September 30, 2020

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

科学分野:

  • ゲリアトリクス ゲリアトリクス
  • 神経学 神経学とは
  • 公衆衛生は公衆衛生である.

背景:

  • 妄想症は,65歳以上の人々の注意力や認知に影響を及ぼす頻繁で重症でしばしば致命的な急性障害です.
  • 重要な費用と死亡率にもかかわらず,認識されていない.
  • 診断は,正式な認知評価と急性症状の発症歴に基づいています.

研究 の 目的:

  • 高齢者の妄想に関する現在の理解をレビューする.
  • 効果的な予防と治療戦略を強調する.
  • 脳の病理生理学と患者の安全性の理解における妄想の役割を強調する.

主な方法:

  • 妄想の診断,予防,治療に関する既存の文献のレビュー.
  • 妄想が脳健康と患者の安全に及ぼす影響の分析.
  • 狂妄症に関連する公衆衛生上の優先事項の議論.

主要な成果:

  • 多成分,非薬理学的アプローチは,妄想の予防のための最も効果的な戦略です.
  • 薬理学的予防や治療の有効性を裏付ける説得力のある証拠はありません.
  • 非薬理学的方法に加えて,鎮静と鎮痛のための薬剤の減少が推奨されます.

結論:

  • 妄想は,脳の脆弱性のマーカーであり,認知障害の潜在的なメカニズムとして機能します.
  • 妄想の対処は,患者の安全性を向上させ,システム全体のプロセス改善を促進するために不可欠です.
  • 公共衛生の取り組みは,改善されたコーディング,払い戻し,研究資金,臨床医と公衆のための教育に焦点を当てるべきです.