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Updated: May 8, 2026

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
07:30

A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

Published on: January 21, 2020

ニトロンとビニルディアゾアセテート間のRh2 (((R-TPCP) 4-触媒化されたエナチオセレクティブ [3+2]-サイクロアディションである

Changming Qin1, Huw M L Davies

  • 1Department of Chemistry, Emory University , 1515 Dickey Drive, Atlanta, Georgia 30322, United States.

Journal of the American Chemical Society
|September 13, 2013
PubMed
まとめ

この研究は,ビニルディアゾアセテートとニトロンの間のロジウム触媒反応を導入し,非対称なサイクロアディション経由でキラル2,5-ジヒドロアイソクサゾールを効率的に生成します. ディロジウム触媒は,この汎用性の高い合成方法に最適であることが証明されました.

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