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サイトプラズミックLPSはカスパース""を活性化させる:TLR4独立性エンド毒性ショックへの影響

Jon A Hagar1, Daniel A Powell, Youssef Aachoui

  • 1Department of Microbiology and Immunology and Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Science (New York, N.Y.)
|September 14, 2013
PubMed
まとめ

細胞質のリポポリサッカリド (LPS) の汚染は,カスパース11の活性化を誘発し,これは重要な先天性免疫反応である. この発見は,細胞内の細菌の病原体を検出するための新しい経路を明らかにします.

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