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Updated: May 7, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
10:17

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

イミダゾールベースのキラルビアリルP,N-リガンドの設計,製造,および実装は,非対称な触媒作用のためのものです

Flavio S P Cardoso1, Khalil A Abboud, Aaron Aponick

  • 1Department of Chemistry, University of Florida , P.O. Box 117200, Gainesville, Florida 32611, United States.

Journal of the American Chemical Society
|September 19, 2013
PubMed
まとめ

研究者らは,5基のヘテロサイクルのキラルバイアリル化合物を生成するための新しい戦略を開発しました. イミダゾールベースのリガンドが合成され,エナチオセレクティブのA(3) 結合反応において非常に有効であることが証明されました.

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Amide Coupling Reaction for the Synthesis of Bispyridine-based Ligands and Their Complexation to Platinum as Dinuclear Anticancer Agents07:20

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Reduction of Alkenes: Asymmetric Catalytic Hydrogenation

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