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Updated: May 1, 2026

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設計されたナノボディによって安定したβ2-アドレノ受容体のアドレナリン活性化構造

Aaron M Ring1,2, Aashish Manglik1, Andrew C Kruse1

  • 1Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305, USA.

Nature
|September 24, 2013
PubMed
まとめ

研究者は,アドレナリンに結合するβ2アドレノ受容体 (β2AR) の活性状態を捉えました. この突破は,リガンドの相性が異なるにもかかわらず,Gタンパク質結合受容体 (GPCRs) の保存された活性化メカニズムを明らかにしています.

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