トランスレーション開始とリボソームバイオゲネシス:推定rRNAヘリケーゼとRPL46の関与

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Updated: Aug 10, 2026

Isolation of Translating Ribosomes Containing Peptidyl-tRNAs for Functional and Structural Analyses
11:19

Isolation of Translating Ribosomes Containing Peptidyl-tRNAs for Functional and Structural Analyses

Published on: February 25, 2011

A B Sachs1, R W Davis

  • 1Department of Biochemistry, Stanford Medical Center, CA 94305.

Science (New York, N.Y.)
|March 2, 1990
PubMed
まとめ

Saccharomyces cerevisiae SPB遺伝子の寒冷感受性突然変異により,ポリア結合タンパク質 (PAB1) がなくても翻訳を開始することができます. これは,リボソーム生体生成の欠陥が,PAB独立した翻訳を可能にする可能性を示唆し,リボソーム組立に関する洞察を提供している.

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