クランベリー製品と尿路感染症の予防
Ruth Jepson1, Jonathan Craig, Gabrielle Williams
1Centre for Population Health Sciences, Scottish Collaboration for Public Health Research and Policy, University of Edinburgh, Scotland. ruth.jepson@ed.ac.uk
JAMA
|October 3, 2013
まとめ
ジュースやサプリメントを含むクランベリー製品は,尿路感染症 (UTI) を予防する効果はないようです. 臨床試験が関連性を示さない理由を理解するために,さらなる研究が必要である.
科学分野:
- 泌尿器科 泌尿器科とは
- 予防医学は,予防的な医療です.
- 薬理学 薬理学とは
背景:
- 尿路感染症 (UTI) は,特に女性の間で一般的です.
- クランベリー製品は,尿路感染症の予防のために,逸話的に推奨されています.
- 尿路感染症の予防におけるクランベリーの有効性を裏付ける科学的証拠は,まだ定かではありません.
研究 の 目的:
- クランベリー製品の消費と尿路感染症 (UTI) の予防との関連性を評価する.
- クランベリー製品の有効性をプラセボまたは尿路感染症の予防のための他の介入と比較するために.
主な方法:
- クランベリー製品 (ジュース,タブレット,カプセル,シロップ) を調査した臨床試験の体系的レビューとメタ分析.
- クランベリー製品を使用した参加者におけるUTI発生率の比較と対照群の比較.
主要な成果:
- クランベリー製品は,分析された臨床試験において,尿路感染症の発生率の低下と関連しているとは認められなかった.
- クランベリー製品の尿路感染症に対する統計的に有意な予防効果は観察されなかった.
結論:
- 現在の臨床試験データは,尿路感染症を予防するためにクランベリー製品の使用を支持していません.
- 観察された関連性の欠如の潜在的な理由には,参加者の遵守に関する問題,製品内の活性化合物の濃度が不十分,または研究における統計力の不十分が含まれます.
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