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Updated: May 12, 2026

An In Vitro Approach to Study Mitochondrial Dysfunction: A Cybrid Model
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Published on: March 9, 2022

ミトコンドリアDNAに外来核酸塩基配列を挿入すると,Neurospora intermediaの衰老を引き起こします

H Bertrand, B S Chan, A J Griffiths

    Cell
    |July 1, 1985
    PubMed
    まとめ

    ニューロスポラのカリロ変種は,転移可能な要素であるkalDNAを宿し,ミトコンドリアDNAを破壊することによって衰老を引き起こす. これは,リボソーム欠乏症と,影響を受けた株の細胞死につながる.

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