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Updated: May 7, 2026

Dissection of Enhancer Function Using Multiplex CRISPR-based Enhancer Interference in Cell Lines
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Dissection of Enhancer Function Using Multiplex CRISPR-based Enhancer Interference in Cell Lines

Published on: June 2, 2018

遺伝子の複製の後,パラログ干渉は転写回路の進化を制約する

Christopher R Baker1, Victor Hanson-Smith, Alexander D Johnson

  • 1Department of Immunology and Microbiology, University of California, San Francisco, CA 94143, USA.

Science (New York, N.Y.)
|October 5, 2013
PubMed
まとめ

遺伝子の複製は,パラログの間の競争的干渉につながり,特に協力的なアセンブリのタンパク質のために. この干渉を解消すると,Mcm1調節器で見られるように,分子複雑性が増加し,重複した遺伝子を安定させます.

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