アジア人,ヒスパニック人,黒人,白人の間で心房細動の発生率
Thomas A Dewland1, Jeffrey E Olgin, Eric Vittinghoff
1Department of Medicine, Division of Cardiology, Electrophysiology Section (T.A.D., J.E.O., G.M.M.) and the Department of Epidemiology and Biostatistics (E.V.), University of California, San Francisco, CA.
Circulation
|October 10, 2013
まとめ
白人人種は,黒人,ヒスパニック,アジア人と比較して,心房細動 (AF) のリスクが高いと関連しています. 白人のAFリスクの増加は,心血管リスク因子が存在しないときに最も顕著です.
科学分野:
- 心臓病学 心臓病学
- エピデミオロジー エピデミオロジー
- 公衆衛生は公衆衛生である.
背景:
- 人種と心房細動 (AF) に関する以前の研究では,主に二分法比較 (白人と黒人) が使用されました.
- これは以前の研究を制限し,白人種がAFリスクを増やすのか,黒人種が保護を与えるのかについて不確実性を残しました.
研究 の 目的:
- 大規模で多様な集団における人種と心房細動 (AF) のリスクとの関連を調査する.
- 白人の人種が他の人種グループと比較してAFリスクの増加と独立して関連しているかどうかを判断する.
- 心血管疾患の危険因子が,人種とAFの関係をどのように変化させるかを探求する.
主な方法:
- カリフォルニア州 (2005年 - 2009年) の病院でのケアのためのヘルスケアコストと活用プロジェクト (HCUP) データベースを使用しました.
- コックス比例リスクモデルを用いた約1400万人の患者集団におけるインシデントAFを調査した.
- 多変量分析における患者の人口統計とAFリスク因子により調整された.
主要な成果:
- 黒人,ヒスパニック,アジア人の個人は,白人と比較して著しく低いAFリスクを示した (HRはそれぞれ0.84,0.78,0.78).
- 白人の個人は,既得心血管リスク因子の欠如で不均衡に高いAFリスクを示しました.
- 白人の間で高まったAFリスクは,併発性疾患の存在で減少または逆転した.
結論:
- 大規模な病院ベースのコホートでは,白人は黒人,ヒスパニック,アジア人と比較して心房細動 (AF) のリスクの増加と関連しています.
- 白人の個人に観察されるAFリスクの上昇は,心血管関連疾患が存在しないときに最も顕著です.
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