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RNA干渉は,哺乳類の抗ウイルス免疫メカニズムとして機能します

Yang Li1, Jinfeng Lu, Yanhong Han

  • 1Department of Plant Pathology and Microbiology, University of California, Riverside, CA 92521, USA.

Science (New York, N.Y.)
|October 12, 2013
PubMed
まとめ

哺乳類RNA干渉 (RNAi) は,抗ウイルス防御として作用する. ノダムラウイルス (NoV) は,この免疫を抑制するためにそのB2タンパク質を使用しますが,B2の損失はウイルス siRNAの生産とマウスのクリアランスを引き起こします.

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