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プロスタグランジンE2は,EP4シグナル伝達経由でダクトス動脈の弾性生成を阻害する

Utako Yokoyama1, Susumu Minamisawa, Aki Shioda

  • 1Cardiovascular Research Institute, Yokohama City University, Yokohama, Japan (U.Y., S.M., A.S., R.I., M.-H.J., Y.I.); the Department of Life Science and Medical Bioscience, Waseda University Graduate School of Advanced Science and Engineering, Tokyo, Japan (S.M., R.I.); the Department of Cell Physiology, Jikei University School of Medicine, Tokyo, Japan (S.M.); the Department of Surgery, Yokohama City University, Yokohama, Japan (M.M.); the Department of Cardiovascular Surgery, Kanagawa Children's Medical Center, Yokohama, Japan (T.A.); the Department of Pharmaceutical Biochemistry, Kumamoto University, Kumamoto, Japan (Y.S.); Cardiovascular Research Institute, Kurume University, Kurume, Japan (H.A.); and the Department of Pharmacology, Kansai Medical University, Osaka, Japan (T.N.).

Circulation
|October 23, 2013
PubMed
まとめ

プロスタグランジンE2 (PGE2) 信号は,成人の循環を確立するための重要なステップであるリシル酸化酵素 (LOX) タンパク質を分解することによって,動脈管 (DA) の弾性繊維形成を抑制します.

キーワード:
弾性 (elasticity) 弾性 (elasticity) とは,弾性 (elasticity) とは,弾性 (elasticity) とは,弾性 (elasticity) とは,弾性 (elasticity) とは,弾性 (elasticity) とは筋肉,滑らかな,滑らかな小児科 小児科プロスタグランディン (Prostaglandins) とはシグナルトランスデュークション信号.

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