関連する実験動画

Updated: May 6, 2026

Monitoring Activation of the Antiviral Pattern Recognition Receptors RIG-I And PKR By Limited Protease Digestion and Native PAGE
12:43

Monitoring Activation of the Antiviral Pattern Recognition Receptors RIG-I And PKR By Limited Protease Digestion and Native PAGE

Published on: July 29, 2014

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PPRタンパク質による単一鎖RNAのモジュール認識のための構造的基礎

Ping Yin1, Quanxiu Li, Chuangye Yan

  • 11] State Key Laboratory of Bio-membrane and Membrane Biotechnology, Tsinghua University, Beijing 100084, China [2] Center for Structural Biology, School of Life Sciences and School of Medicine, Tsinghua-Peking Center for Life Sciences, Tsinghua University, Beijing 100084, China [3].

Nature
|October 29, 2013
PubMed
まとめ

ペンタトリコペプチドリピート (PPR) タンパク質は,特定のRNA配列を結合する. この研究は,トウモロコシPPR10の結晶構造を明らかにし,潜在的なバイオテクノロジーの応用のためのRNAを認識する方法を解明しました.

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Nucleic Acid Structure

The pentose sugar in DNA is deoxyribose, while in RNA the pentose sugar is ribose. The difference between the sugars is the presence of the hydroxyl group on the ribose's second carbon and a hydrogen on the deoxyribose's second carbon. The phosphate residue attaches to the hydroxyl group of the 5′ carbon of one sugar and the hydroxyl group of the 3′ carbon of the sugar of the next nucleotide, which forms  a 5′ to 3′ phosphodiester linkage.
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Types of RNA

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RNA Interference

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