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Updated: May 6, 2026

PCR Mutagenesis, Cloning, Expression, Fast Protein Purification Protocols and Crystallization of the Wild Type and Mutant Forms of Tryptophan Synthase
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PCR Mutagenesis, Cloning, Expression, Fast Protein Purification Protocols and Crystallization of the Wild Type and Mutant Forms of Tryptophan Synthase

Published on: September 26, 2020

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環境からのトリプトファン・ダイマー遺伝子群の発見と合成リファクタリング

Fang-Yuan Chang1, Melinda A Ternei, Paula Y Calle

  • 1Laboratory of Genetically Encoded Small Molecules, Howard Hughes Medical Institute, The Rockefeller University , 1230 York Avenue, New York, New York 10065, United States.

Journal of the American Chemical Society
|November 1, 2013
PubMed
まとめ

研究者らは,環境DNA (eDNA) を分析することによって,新しい細菌のトリプトファン・ディマー (TD) 生物合成遺伝子クラスタを発見した. このアプローチは,新しい細胞毒素を特定し,既知の多種多様性および土壌環境における潜在能力を拡大しました.

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