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Updated: Jan 20, 2026

Studying Copper Nanoparticle-Induced Programmed Cell Death in Bacteria
08:22

Studying Copper Nanoparticle-Induced Programmed Cell Death in Bacteria

Published on: May 16, 2025

544

タイプ2の銅中心を持つメタロペプチドのDe novo設計:還元ポテンシャルと窒素還元酵素の活性化の調節

Fangting Yu1, James E Penner-Hahn, Vincent L Pecoraro

  • 1Department of Chemistry, University of Michigan , 930 North University Avenue, Ann Arbor, Michigan 48109-1055, United States.

Journal of the American Chemical Society
|November 5, 2013
PubMed
まとめ

デノボペプチドの設計は,銅中心付近の有電荷アミノ酸残留が,酸化還元酵素の活性を調節する方法を明らかにした. これらの残基を改変すると,銅の結合,還元ポテンシャル,および触媒率に重大な影響があり,メタロ酵素工学に洞察を提供します.

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