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Updated: May 6, 2026

Isolation and Characterization of Dendritic Cells and Macrophages from the Mouse Intestine
09:25

Isolation and Characterization of Dendritic Cells and Macrophages from the Mouse Intestine

Published on: May 21, 2012

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ヒストン脱エチラゼ3の座標は,共生細菌に依存する腸内ホメオスタシスである

Theresa Alenghat1, Lisa C Osborne, Steven A Saenz

  • 11] Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA [2] Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA [3] Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

Nature
|November 5, 2013
PubMed
まとめ

腸内細胞のヒストン脱酸化酵素3 (HDAC3) は,腸内ホメオスタシスの維持に不可欠です. その欠如は,抗微生物防御を妨害し,炎症に対する感受性を高め,宿主-微生物の相互作用におけるその役割を強調します.

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