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Updated: May 1, 2026

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer
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Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer

Published on: July 29, 2010

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結腸直腸癌および子宮内膜癌ゲノムにおけるマイクロサテライトの不安定性の風景

Tae-Min Kim1, Peter W Laird, Peter J Park

  • 1Center for Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA; Cancer Evolution Research Center, College of Medicine, The Catholic University of Korea, Seoul 137-701, Korea.

Cell
|November 12, 2013
PubMed
まとめ

DNA修復の欠陥によって引き起こされるマイクロサテライトの不安定性 (MSI) は,大腸癌と子宮内膜癌の腫瘍特異的なパターンを示しています. このゲノム不安定性は遺伝子発現に影響を与え,クロマチンの組織によって影響を受けます.

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