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Updated: May 6, 2026

Nucleocapsid Annealing-Mediated Electrophoresis NAME Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors
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HIV-1核カプシドタンパク質は,テトラ分子抗パラレルG-クアドルプレックス形成の分子チャペロンとして機能する

Arivazhagan Rajendran1, Masayuki Endo, Kumi Hidaka

  • 1Department of Chemistry, Graduate School of Science, Kyoto University , Kitashirakawa-oiwakecho, Sakyo-ku, Kyoto 606-8502, Japan.

Journal of the American Chemical Society
|November 15, 2013
PubMed
まとめ

HIV-1核カプシドタンパク質 (NCps) は,核酸チャペロンとして作用する. この研究では,DNA オリガミを使用して,NCp ステキオメトリーとリアルタイム G-クアドルプレックス形成を明らかにし,エイズ薬の設計を支援しました.

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