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Updated: May 6, 2026

Identification of Mediators of T-cell Receptor Signaling via the Screening of Chemical Inhibitor Libraries
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Themisは,T細胞発達のポジティブ・ネガティブ・セレクションのシグナル値を設定する

Guo Fu1, Javier Casas2, Stephanie Rigaud3

  • 1Department of Immunology and Microbial Science, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037, USA.

Nature
|November 15, 2013
PubMed
まとめ

Themisタンパク質は,T細胞発達の過程でT細胞受容体 (TCR) 信号の強さを調節する. 弱い信号を弱めることでT細胞の適切な陽性選択を保証し,感染病原体の認識を可能にします.

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