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グルコキナーゼ調節タンパク質小分子破壊剤の抗糖尿病効果

David J Lloyd1, David J St Jean2, Robert J M Kurzeja2

  • 1Department of Metabolic Disorders, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, USA.

Nature
|November 15, 2013
PubMed
まとめ

研究者らは,グルコキナーゼ調節タンパク質とグルコキナーゼの相互作用を妨害し,糖尿病を患っているネズミの血糖を正常化する新しい化合物を特定しました. このアプローチは,低血糖症のリスクが低下した2型糖尿病の治療の可能性を示しています.

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