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Updated: May 6, 2026

Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice
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Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice

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コメンサル細菌によって生成されるメタボライトは,外周的調節性T細胞の生成を促進します

Nicholas Arpaia1, Clarissa Campbell1, Xiying Fan1

  • 11] Howard Hughes Medical Institute and Ludwig Center at Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA [2] Immunology Program, Memorial Sloan-Kettering Cancer Center, New York, New York 10065, USA.

Nature
|November 15, 2013
PubMed
まとめ

ブチラートのような微生物の短鎖脂肪酸は,腸内の抗炎症調節性T細胞 (Treg) の発育を促進します. これは,腸内細菌の代謝物が免疫システムのバランスと腸内ホメオスタシスにどのように影響するかを強調しています.

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