不眠症の症状と死亡率との関連:米国の男性を対象とした将来性研究
Yanping Li1, Xuehong Zhang, John W Winkelman
1Channing Division of Network Medicine (Y.L., X.Z., F.B.H., M.S., J.M., X.G.) and Division of Sleep Medicine, Department of Medicine (J.W.W., S.R.), Brigham and Women's Hospital and Harvard Medical School, Boston, MA; Departments of Nutrition (F.B.H., M.S., X.G.) and Epidemiology (F.B.H., M.S.), Harvard School of Public Health, Boston, MA.
Circulation
|November 15, 2013
まとめ
睡眠開始の困難や回復しない睡眠などの不眠症の症状は,男性における死亡リスクのわずかに増加と関連しています. この前向きな研究は,持続的な睡眠障害の潜在的な健康上の影響を強調しています.
科学分野:
- ゲロントロジーはゲロントロジーの学科です.
- スリープ・メディシン (睡眠医学)
- エピデミオロジー エピデミオロジー
背景:
- 不眠症は高齢者に多く見られ,死亡リスクと相関する可能性があるが,既存の証拠は矛盾している.
- 不眠症と死亡率に関する以前の研究は,異なった結果をもたらし,さらなる調査を必要とした.
研究 の 目的:
- 米国の男性の大集団における不眠症の症状と死亡リスクとの関連を将来的に調査する.
- 睡眠開始または維持の困難などの特定の不眠症の症状が,死亡率の増加を予測しているかどうかを判断する.
主な方法:
- ヘルスプロフェッショナルのフォローアップ研究から23,447人の米国男性を対象とした前向きなコホート研究で,ベースラインでがんがない.
- 不眠症の症状に関するデータは2004年に収集され,2010年まで追跡調査を行い,2025人の死亡者を特定しました.
- 死亡リスクを評価するために,年齢,ライフスタイル要因,慢性疾患に関する多変量調整が行われました.
主要な成果:
- 睡眠を開始する困難は,総死亡率の25%のリスク増加と関連していました (HR,1.25; 95% CI,1.04-1.50).
- 非回復的な睡眠は,全死亡率の24%のリスク増加と関連していた (HR,1.24;95%CI,1.05-1.46).
- 睡眠開始の困難と非回復的睡眠は,心血管疾患による死亡リスクの増加とも関連していました.
結論:
- 特定の不眠症の症状,特に睡眠開始の困難と回復しない睡眠は,死亡率のわずかに高いリスクと関連しています.
- これらの発見は,特定の睡眠障害と男性における長期的な健康結果との関連を示唆しています.
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