生き残った人によって引き起こされた異常なプロイディは,胞性腎臓と動脈瘤の形成に寄与する

Wissam A Aboualaiwi1, Brian S Muntean, Shobha Ratnam

  • 1Department of Pharmacology (W.A.A., S.M.N.), Department of Medicinal and Biological Chemistry (B.S.M., S.M.N.), Department of Medicine (S.R., S.M.N.), Center for Hypertension and Personalized Medicine (B.J., S.M.N.), Department of Biochemistry and Cancer Biology (L.L.), and Department of Pathology (R.L.B.), University of Toledo, Toledo, OH; Department of Emergency and Intensive Care, ProMedica Sponsored Research, Toledo, OH (I.R.); Departments of Medicine (B.S.H.) and Medical and Molecular Genetics (R.L.B.), Indiana University School of Medicine, Indianapolis; UCL Institute of Ophthalmology, University College London, London, UK (M.F.); Ontario Cancer Institute, University Health Network, Toronto, ON, Canada (T.W.M.); and Department of Medicine, Brigham and Women's Hospital, Boston, MA (J.Z.).

Circulation
|November 16, 2013
PubMed
まとめ

多囊性腎臓病は,胞性腎臓と,低生存率表現に関連した血管動脈瘤を含む. 生存者を復元すると腎臓キスタが回復し,腎臓と血管の欠陥の共通の経路が明らかになる.

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