関連する実験動画

Updated: May 5, 2026

A High-throughput-compatible FRET-based Platform for Identification and Characterization of Botulinum Neurotoxin Light Chain Modulators
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A High-throughput-compatible FRET-based Platform for Identification and Characterization of Botulinum Neurotoxin Light Chain Modulators

Published on: December 27, 2013

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ボツリヌム神経毒素Aによるシナプス水泡タンパク質2Cの認識のための構造的基礎

Roger M Benoit1, Daniel Frey2, Manuel Hilbert2

  • 1Laboratory of Biomolecular Research, Paul Scherrer Institut, CH-5232 Villigen PSI, Switzerland.

Nature
|November 19, 2013
PubMed
まとめ

ボトリン神経毒素A (BoNT/A) は,その受容体結合ドメインを通じてSV2Cと結合する. BoNT/A-SV2Cの相互作用に関するこの構造的洞察は,新しい抗毒素および治療用毒素の変種の開発に役立ちます.

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