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Updated: May 5, 2026

Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle
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Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle

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筋肉ミトホルメシスは,インスリンシグナル伝達の全身抑制を通じて長寿を促進します

Edward Owusu-Ansah1, Wei Song, Norbert Perrimon

  • 1Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.

Cell
|November 19, 2013
PubMed
まとめ

ドロソフィラの軽度の筋肉ミトコンドリア損傷は,補償的ストレス反応を活性化することによって,機能を保ち,寿命を延ばします. これは,ミトコンドリアの展開タンパク質応答 (UPR) とインスリン型の成長因子結合タンパク質7を含むもので,老化および代謝疾患に対する潜在的な治療標的を示唆する.

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