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Updated: May 5, 2026

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
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Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach

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ピリジンとディアジンの選択的C-H化は,古典的なアミネーション反応に触発されたものです

Patrick S Fier1, John F Hartwig

  • 1Department of Chemistry, University of California, Berkeley, CA 94720, USA.

Science (New York, N.Y.)
|November 23, 2013
PubMed
まとめ

新しい安全な方法により,ピリジンなどの窒素を含むヘテロサイクルの選択的化が可能になる. このアプローチでは,軽度な条件下で銀 (((II) フッ素を使用し,貴重なフッ素化合物を生成します.

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Arenediazonium substitution reactions occur when the diazonium group is substituted by various functional groups such as halides, hydroxyl, nitrile, etc. For instance, arenediazonium salts react with copper(I) salts of chloride, bromide, or cyanide to form corresponding aryl chlorides, bromides, and nitriles. These reactions are named Sandmeyer reactions. Although the mechanism of this reaction is complicated, as illustrated in Figure 1, they are believed to progress via an aryl copper...
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