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Updated: May 5, 2026

Right Ventricular Systolic Pressure Measurements in Combination with Harvest of Lung and Immune Tissue Samples in Mice
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肺動脈高血圧におけるDNA損傷シグナリングの役割

Jolyane Meloche1, Aude Pflieger, Mylène Vaillancourt

  • 1Department of Medicine, Laval University, Pulmonary Hypertension Research Group, IUCPQ Research Centre, Québec, Canada (J.M., A.P., M.V., F.P., C.G., A.C., S.B.-B., E.T., C.C., S.P., S.B.); and Vascular Biology Research Group, Department of Medicine, University of Alberta, Edmonton, Canada (R.P., S.Z., E.D.M.).

Circulation
|November 26, 2013
PubMed
まとめ

肺動脈高血圧 (PAH) はDNA損傷と炎症を伴う. ポリ・・・ADP-リボース) ポリメラーゼ-1 (PARP-1) をターゲットにすることで,PAHを逆転させ,新たな治療戦略を提供することが期待されています.

キーワード:
DNA損傷によるDNA損傷です.PARP1タンパク質,ヒトマイクロRNAs (マイクロRNAs) とは肺動脈高血圧 肺動脈高血圧 肺動脈高血圧 肺動脈高血圧

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