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Updated: May 5, 2026

Anaerobic Protein Purification and Kinetic Analysis via Oxygen Electrode for Studying DesB Dioxygenase Activity and Inhibition
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酵素構造:オロチジン5'-モノフォファートデカルボキシラーゼの活性化オキシディアニオン結合領域

Krisztina Spong1, Tina L Amyes, John P Richard

  • 1Department of Chemistry, University at Buffalo, SUNY , Buffalo, New York 14260-3000, United States.

Journal of the American Chemical Society
|November 27, 2013
PubMed
まとめ

オロチジン5'-モノフォスファートデカルボキシラーゼ (OMPDC) は,酵素触媒を活性化するために四面体オキシディアニオンを使用します. これらのアニオンは,移行状態を安定させ,ピリミジン生物合成の重要なステップであるオロタートのデカルボキシル化を促進します.

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