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Updated: May 5, 2026

In Vivo Augmentation of Gut-Homing Regulatory T Cell Induction
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dendritic 細胞の栄養センサ GCN2 のワクチン活性化は,抗原プレゼンテーションを強化します

Rajesh Ravindran1, Nooruddin Khan1,2, Helder I Nakaya1,3

  • 1Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, 954 Gatewood Road, Atlanta, GA 30329, USA.

Science (New York, N.Y.)
|December 7, 2013
PubMed
まとめ

黄熱ワクチンは,免疫細胞の反応を強化する,制御不能の2キナーゼ (GCN2) を一般的に活性化します. この発見は, dendritic 細胞における GCN2 プログラミングが,ウイルス感染症に対する適応免疫力を高める方法を示しています.

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