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Updated: Aug 1, 2026

Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development
09:32

Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development

Published on: June 15, 2017

8.0K

オプトジェネティクスを使って,Ras/Erkモジュールによる信号伝送のダイナミック制御を調査する

Jared E Toettcher1, Orion D Weiner, Wendell A Lim

  • 1Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA 94158-2517, USA; Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA 94158-2517, USA; Department of Biochemistry, University of California San Francisco, San Francisco, CA 94158-2517, USA.

Cell
|December 10, 2013
PubMed
まとめ

研究者は,細胞信号伝達経路を正確に制御するために光遺伝学を使用し,Ras-Erk経路がどのように情報を伝達し,信号のタイミングに基づいて異なる細胞結果を生成するかを明らかにしました. この方法は,複雑な細胞のコミュニケーションの理解を高めます. キーワード:光遺伝学,細胞シグナル伝達,Ras-Erk経路,細胞結果.

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