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Updated: Aug 11, 2026

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マクロファグ細胞毒性:L-アルギニンデミナーゼとイミノ窒素酸化によるニートリートへの作用

J B Hibbs, R R Taintor, Z Vavrin

    Science (New York, N.Y.)
    |January 23, 1987
    PubMed
    まとめ

    細胞毒性活性化マクロファージは,L-アルギニン経路を通じて腫瘍細胞の代謝を阻害する. この経路は,マクロファージ媒介による腫瘍細胞死において極めて重要なL-シトルリンとニートリットを合成する.

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