イノシトール1,4,5-トリフォスファートによって活性化されたイオンチャネルは,ヒトTリンパ球の血膜に存在します

Nature
|March 19, 1987
PubMed
まとめ

イノシトール1,4,5-トリスホスファート (Ins(1,4,5) P3) は,Tリンパ球内のトランスメブランカルシウムチャネルを直接活性化する. この発見は,カルシウム流入を媒介することによって,T細胞活性化における第2のメッセンジャーとしての役割を裏付けている.

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