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Detection of Protein S-Acylation using Acyl-Resin Assisted Capture
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動的アシルキャリアタンパク質を脂肪酸のバイオシンセシスに閉じ込めます

Chi Nguyen1, Robert W Haushalter2, D John Lee2

  • 11] Departments of Molecular Biology and Biochemistry, Chemistry, and Pharmaceutical Sciences, University of California, Irvine, California 92697, USA [2].

Nature
|December 24, 2013
PubMed
まとめ

アシルキャリアタンパク質 (ACP) は,脂肪酸バイオシンセシス中に脂質鎖を安定させ,輸送する. 新しいクロスリンク方法により,AcpP-FabA複合体の構造が明らかになり,脱水に不可欠なACPダイナミクスを示し,様々な代謝経路に適用できる可能性がある.

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