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Updated: May 4, 2026

Determination of Protein-ligand Interactions Using Differential Scanning Fluorimetry
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Determination of Protein-ligand Interactions Using Differential Scanning Fluorimetry

Published on: September 13, 2014

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リガンド濃度は,結合タンパク質の折り畳みと結合の経路を調節する

Kyle G Daniels1, Nam K Tonthat, David R McClure

  • 1Department of Biochemistry, Duke University Medical Center , Durham, North Carolina 27710, United States.

Journal of the American Chemical Society
|December 25, 2013
PubMed
まとめ

リンガンド結合とタンパク質構成の変化は濃度に依存する. この研究は,形状選択と誘導的適合の間の議論が偽の二分論であり,そのメカニズムはリガンドレベルによって異なることを示しています.

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