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Updated: May 4, 2026

Cholesterol Efflux Assay
07:54

Cholesterol Efflux Assay

Published on: March 6, 2012

29.4K

CXCR7の活性化は,動脈硬化症を制限し,脂肪組織におけるコレステロールの吸収を増加させることで,高脂血症を改善します

Xiaofeng Li1, Mengyu Zhu, Mark E Penfold

  • 1Institute for Molecular Cardiovascular Research (X.L., R.R.K., A.T., K.H., S.A., Z.W., M.v.Z., C.W., A.S.), Core Facility Two-Photon Imaging, Interdisciplinary Center for Clinical Research Aachen (S.K.), and Experimental Molecular Imaging (F.G., F.K.), RWTH Aachen University, Aachen, Germany; Institute for Cardiovascular Prevention, Ludwig Maximilians University Munich, Munich, Germany (M.Z., R.R.K., K.H., C.W., A.S.); ChemoCentryx Inc, Mountain View, CA (M.E.P., T.J.S.); Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands (M.v.Z., C.W.); and Munich Heart Alliance, Munich, Germany (C.W., A.S.).

Circulation
|December 31, 2013
PubMed
まとめ

ケモカイン受容体CXCR7 (C-X-C ケモカイン受容体タイプ7) は,動脈硬化症において重要な役割を果たします. CCX771のようなリガンドでCXCR7を標的にすることは,コレステロールを低下させ,血管疾患の進行を減少させます.

キーワード:
動脈硬化症 (動脈動脈硬化症) について冠動脈リステノシスハイパーコレステロール血症

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