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Genetic Analysis of Hereditary Transthyretin Ala97Ser Related Amyloidosis
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リウマチ性関節炎の遺伝学は,生物学と薬剤発見に寄与しています

Yukinori Okada1, Di Wu2, Gosia Trynka1

  • 11] Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. [2] Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. [3] Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts 02142, USA.

Nature
|January 7, 2014
PubMed
まとめ

この研究では,新たに42のリウマチ性関節炎 (RA) リスク遺伝子を特定し,合計101. これらの発見は,遺伝データを生物学的情報と統合し,RAの病原性に関する理解を深め,薬剤発見を導きます.

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