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Updated: May 4, 2026

Regioselective O-Glycosylation of Nucleosides via the Temporary 2',3'-Diol Protection by a Boronic Ester for the Synthesis of Disaccharide Nucleosides
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Regioselective O-Glycosylation of Nucleosides via the Temporary 2',3'-Diol Protection by a Boronic Ester for the Synthesis of Disaccharide Nucleosides

Published on: July 26, 2018

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ヌクレオフィール触媒による再生性グリコシル化

Swati S Nigudkar1, Keith J Stine, Alexei V Demchenko

  • 1Department of Chemistry and Biochemistry, University of Missouri-St. Louis , One University Boulevard, St. Louis, Missouri 63121, United States.

Journal of the American Chemical Society
|January 8, 2014
PubMed
まとめ

この研究では,3,3-difluoroxindole (HOFox) -mediated glycosylation (3,3-difluoroxindole (HOFox) -mediated glycosylation) が導入され,これは,glycosylドナーを in situ 合成するための新しい方法である. 重要なイノベーションは,これらのドナーの再生合成と活性化であり,効率的なグリコシル化反応を可能にします.

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