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UvrDは,RNAポリメラーゼを後方に引っ張ることによってDNA修復を促進します

Vitaly Epshtein1, Venu Kamarthapu2, Katelyn McGary3

  • 11] Department of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, New York 10016, USA [2].

Nature
|January 10, 2014
PubMed
まとめ

Escherichia coli UvrDヘリケーゼは,転写中にRNAポリメラーゼを逆行させ,DNAの損傷を暴露させます. このメカニズムは,核酸切除修復がDNA損傷にアクセスし,修復し,ゲノムの完全性を維持することを可能にします.

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