ラキテス症候群 (RACITES) とは
Charlotte Jane Elder1, Nicholas J Bishop1
1University of Sheffield, Academic Unit of Child Health, Sheffield Children's Hospital, Western Bank, Sheffield, UK.
Lancet (London, England)
|January 14, 2014
まとめ
世界的な骨疾患である症は,主にビタミンDの不足によって引き起こされ,低リン酸レベルにつながります. 現在の乳幼児のビタミンDガイドラインは不明確であり,この状態を防ぐために改訂する必要があります.
科学分野:
- 小児科は小児科です.
- 栄養科学とは,栄養科学である.
- エンドクリノロジー エンドクリノロジー
背景:
- 歴史的に"イングランド病"として知られている症は,依然として世界的な健康問題である.
- 主な原因は,不十分なビタミンDであり,成長板と骨表面のリン酸欠乏につながります.
- リン酸代謝に影響する遺伝性疾患は,ミネラルホメオスタシスの複雑さを強調しています.
研究 の 目的:
- 乳児に対する現在のビタミンDサプリメントのガイドラインの矛盾と明確性の欠如に対処するために.
- 広範囲に広がった病の発生率を効果的に撲滅するために,改訂された勧告の必要性を強調する.
主な方法:
- ラキットの病因とビタミンDの代謝に関する既存の文献のレビュー.
- 乳幼児の栄養とビタミンDサプリメントの現在のグローバルガイドラインの分析.
- 骨のミネラライゼーションに対するリン酸利用量の影響の評価.
主要な成果:
- ビタミンDの不十分な供給は,世界中でラキットの主要な原因です.
- 乳児のビタミンDに関する既存のガイドラインは,断片的で矛盾しており,病気の根絶には不十分です.
- リン酸代謝の理解は,ラキティスの病原性に対処するために不可欠です.
結論:
- 乳児に対する現在のビタミンDの推奨は,大幅な明確化と改訂を必要としています.
- ビタミンDの提供に統一され,証拠に基づいたアプローチが,ラキスを根絶するために必要である.
- 骨の健康におけるリン酸塩の役割に関するさらなる研究が必要である.
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