PRDM16とベージュの脂肪の除去は代謝機能障害を引き起こし,皮下脂肪から内臓脂肪へのスイッチを起こす

Paul Cohen1, Julia D Levy2, Yingying Zhang2

  • 1Dana-Farber Cancer Institute and Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA; Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.

Cell
|January 21, 2014
PubMed
まとめ

共同調節タンパク質PRDM16はベージュ色脂肪細胞機能に不可欠であり,肥満やインスリン抵抗性から保護します. PRDM16の喪失は,有益な皮下脂肪を有害な内臓脂肪に変換する.

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