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Updated: May 3, 2026

Dissolution Dynamic Nuclear Polarization Instrumentation for Real-time Enzymatic Reaction Rate Measurements by NMR
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Published on: February 23, 2016

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タンパク質の溶液NMRにおけるダイナミックな核極化のためのプラットフォームとしての逆ミセル

Kathleen G Valentine1, Guinevere Mathies, Sabrina Bédard

  • 1Johnson Research Foundation and Department of Biochemistry and Biophysics, University of Pennsylvania , Philadelphia, Pennsylvania 19104-6059.

Journal of the American Chemical Society
|January 25, 2014
PubMed
まとめ

ダイナミックな核極化 (DNP) は,水に急性極化,そしてバイオ分子に急性極化を転送することによって,溶液NMR無感性を克服します. タンパク質をリバースミセルで封じ込めることで,効率的なDNPが可能になり,NMRの感受性を大幅に高めます.

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