調,.

Menachem Fromer1, Andrew J Pocklington2, David H Kavanagh2

  • 11] Division of Psychiatric Genomics in the Department of Psychiatry, and Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA [2] Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts 02142, USA.

Nature
|January 28, 2014
PubMed
まとめ

活性調節型細胞骨組み関連タンパク質 (ARC) とN-メチル-d-アスパラテート受容体 (NMDARs) のようなポストシナプスタンパク質の遺伝子に影響を与える小さなデノボ変異は,統合失調症のリスクと関連しています. これらの遺伝的発見は,他の神経発達障害と共通のメカニズムを明らかにします.

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